Eric J. Lenze, MD

Professor of Psychiatry

  • Phone: 314-362-5154
  • Fax: 314-747-1160

Professional Experience

Dr. Lenze has been the Director and a Principal Investigator of the lab since its conception. His area of interest is improving brain health for individuals over the age of 60. Dr. Lenze is currently working on research studies on healthy aging, called MEDEX, and treatment-resistant depression, called Optimum. In the near future, he hopes to give older participants better access to our studies by conducting them through phone/tablet applications.

Education & Training

  • Bachelor of Arts, Washington University in St. Louis, Biology and Philosophy
  • Doctor of Medicine, Washington University School of Medicine
  • Residency, Barnes-Jewish Hospital at Washington University School of Medicine, Psychiatry
  • Fellowship, Intervention Research Center for Late-Life Mood Disorders at University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic

Media Mentions and Awards

Best Doctors in America (2005-present)

Resident Mentoring Award from Washington University Department of Psychiatry (2012)

Current Research Studies


Anxiety and Depression

Rollman BL, Belnap BH, Mazumdar S, Abebe KZ, Karp JF, Lenze EJ, Schulberg HC, (2017 Mar). Telephone-Delivered Stepped Collaborative Care for Treating Anxiety in Primary Care: A Randomized Controlled Trial. J Gen Intern Med. 32(3): 245-255. Read more.

Rawson KS, Dixon D, Civitelli R, Peterson TR, Mulsant BH, Reynolds CF, Lenze EJ, (2017 Sep). Bone Turnover with Venlafaxine Treatment in Older Adults with Depression. J Am Geriatr Soc. 65(9): 2057-2063. Read more.

Cristancho P, Lenze EJ, Dixon D, Miller JP, Mulsant BH, Reynolds CF, Butters MA, (2018 Apr). Executive Function Predicts Antidepressant Treatment Noncompletion in Late-Life Depression. J Clin Psychiatry. 79(3). Read more.

Wetherell JL, Hershey T, Hickman S, Tate SR, Dixon D, Bower ES, Lenze EJ, (2017 Jul). Mindfulness-Based Stress Reduction for Older Adults With Stress Disorders and Neurocognitive Difficulties: A Randomized Controlled Trial. J Clin Psychiatry. 78(7): e734-e743. Read more.

Healthy Aging

Ashton NJ, Hye A, Leckey CA, Jones AR, Gardner A, Elliott C, Wetherell JL, Lenze EJ, Killick R, Marchant NL, (2017 06). Plasma REST: a novel candidate biomarker of Alzheimer’s disease is modified by psychological intervention in an at-risk population. Transl Psychiatry. 7(6): e1148. Read more.

Iaboni A, Rawson K, Burkett C, Lenze EJ, Flint AJ, (2017 09). Potentially Inappropriate Medications and the Time to Full Functional Recovery After Hip Fracture. Drugs Aging. 34(9): 723-728. Read more.

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