Washington University trial studies antidepressant Fluvoxamine as treatment for Long COVID symptoms (Links to an external site)

ST. LOUIS (KMOV) -A clinical trial at the Washington University School of Medicine is studying the impact of an antidepressant on long COVID symptoms.

Specifically, the study is examining whether Fluvoxamine, a medication used to treat depression and obsessive-compulsive disorder, can relieve problems with “brain fog” and other neurological conditions associated with lingering symptoms.

$6.2 million grant to fund Center for Perioperative Mental Health (Links to an external site)

Clinicians and researchers at Washington University School of Medicine in St. Louis have received a four-year, $6.2 million grant from the National Institute of Mental Health to launch a center designed to help improve mental health in surgery patients, particularly older surgery patients. The center will conduct studies to identify and treat depression and anxiety in surgical patients. This new center is the first NIH-funded center of its kind in the United States.

Update on our study of an early treatment COVID-19

Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19 A Randomized Clinical Trial Eric J. Lenze, MD1; Caline Mattar, MD2; Charles F. Zorumski, MD1; Angela Stevens, BA1; Julie Schweiger1; Ginger E. Nicol, MD1; J. Philip Miller, AB3; Lei Yang, MPH, MSIS1; Michael Yingling, MS1; Michael S. Avidan, MBBCh4; Angela M. Reiersen, MD, MPE1JAMA. Published online November 12, 2020. doi:10.1001/jama.2020.22760

Goal-oriented rehab improves recovery in older adults (Links to an external site)

Goal-oriented, motivational physical and occupational therapy helps older patients recover more fully from broken hips, strokes and other ailments that land them in skilled nursing facilities for rehabilitation, according to new research at Washington University School of Medicine in St. Louis.

Dr. Eric Lenze weighs in on depression in older adults for The St. Louis American (Links to an external site)

For some older adults, seeking help for depression may be stressful or embarrassing. Some people can’t find the words to describe how they feel, which can make them feel even more alone. Primary care physicians are usually the first health care provider older adults speak with about their stress, mood, anxiety, loneliness, and concerns about their future.

Jennifer Blome of 550 KTRS interviews Dr. Lenze

In honor of Mental Health Awareness Month, we shared information about our healthy aging studies for adults ages 60+ on-air with Jennifer Blome of The Big 550 KTRS. Listen to the full recording or read the transcript below. TRANSCRIPT This radio interview aired on May 14, 2018. Jennifer Blome (The Big 550 KTRS): There is […]

Psychotropic Drugs and Falls in Older Adults (Links to an external site)

In the elderly, falls are a common and important problem. One of the most feared consequences of falling is a hip fracture. Other consequences include other fractures, head injuries, and less serious injuries that can nonetheless impair function and quality of life.

Hard-to-treat depression in seniors focus of $13.5 million study (Links to an external site)

“Older adults who are prescribed antidepressants often find that they don’t get better with the first or second medication they are prescribed,” said principal investigator Eric J. Lenze, MD, a professor of psychiatry. “So what should they get? This will be the largest and, we hope, the definitive study to answer that question. This study will show us which treatments work best and which are safest, and it will help us personalize treatment.”